People taking obesity drugs Ozempic and Wegovy gain weight once they stop medication
Publishing timestamp: 2023-03-30 12:40:58
Summary
Novo Nordisk's senior vice president of global drug discovery, Karin Conde-Knape, stated that patients taking Novo Nordisk's obesity drugs, Ozempic or Wegovy, will regain weight after stopping the medication. The rate of weight gain varies depending on the individual, but available data suggests that most individuals will recover most of their weight within five years of stopping the drug, and roughly 50% of their weight after two to three years. Conde-Knape explained that the drugs mimic a hormone produced in the gut called GLP-1, which signals to the brain when a person is full, but they do not rewire the neural networks to define a new body weight setpoint. Novo Nordisk still needs to conduct more investigations and clinical trials to understand what drives the rates of weight gain.
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